Autologous Graft Thickness Affects Scar Contraction and Quality in a Porcine Excisional Wound Model
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چکیده
منابع مشابه
Autologous Graft Thickness Affects Scar Contraction and Quality in a Porcine Excisional Wound Model
BACKGROUND Texture, color, and durability are important characteristics to consider for skin replacement in conspicuous and/or mobile regions of the body such as the face, neck, and hands. Although autograft thickness is a known determinant of skin quality, few studies have correlated the subjective and objective characters of skin graft healing with their associated morphologic and cellular pr...
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excessive scarring; paralleling the process in tendon reconstruction of the hand. Inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. Methods: Thirty female rats (~200 g) were randomly distributed into two groups (n=15...
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The response to major burn injury includes systemic release of mediators that may have an effect on wound healing. The authors evaluated the effect of a burn injury on the contraction of an excisional wound adjacent to the burn, and the effect of plasma derived from burn-injured animals on the contraction of the fibroblast-populated collagen matrix (FPCM). Nine rats (90-100 days old) under anes...
متن کاملThe relation between wound contraction, scar formation and regeneration
Introduction Healing of deep skin wounds in the adult mammal takes place by the processes of wound contraction and scar formation. There is evidence that scar formation is secondary to contraction. Efforts to block scar formation can therefore benefit from strategies for blocking contraction. In this review we provide a semiquantitative description of healing outcomes based on the wound closure...
متن کاملComparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft
BACKGROUND Platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. The primary objective of this study was to use autologous platelet rich plasma (PRP) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. METHODS In a single ...
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ژورنال
عنوان ژورنال: Plastic and Reconstructive Surgery - Global Open
سال: 2015
ISSN: 2169-7574
DOI: 10.1097/gox.0000000000000426